Hypertrophic Cardiomyopathy Risk: Genetic Variants and Left Ventricular Wall Thickness in Relatives
Hypertrophic cardiomyopathy (HCM) is a common inherited cardiac condition, and family screening is a key recommendation in current guidelines. A retrospective study of 1,230 relatives from 531 families screened at inherited cardiomyopathy clinics in Eastern Denmark (2006-2023) revealed a diagnostic yield of 26% at the initial visit, with an additional 4% of relatives developing HCM during a 7-year follow up.
Heart Failure and Cancer: HFSA Statement Highlights Shared Risks and Multidisciplinary Care Needs
A recent statement from the Heart Failure Society of America highlights the link between heart failure (HF) and cancer, with shared mechanisms driving both conditions. Published in the Journal of Cardiac Failure, it emphasizes the need for coordinated care between cardiology and oncology, standardized cardiac imaging protocols, and efforts to address treatment disparities.
Two-step Screening Could Prevent Heart Failure in Diabetes
According to a study presented on cardiometabolic papers that were previously published in Circulation, assessment that used the WATCH-DM score, followed by N-terminal pro-B-type natriuretic peptide testing, identified approximately 90% of patients with diabetes who would benefit from an SGLT2 inhibitor to prevent heart failure.
Study Shows 38% Drop in Pediatric Heart Transplant Wait-List Mortality
Mortality rates for children awaiting heart transplants have significantly decreased over the past two decades, with a 38% reduction in wait-list mortality from 1999 to 2023.
Podcast: Iron Repletion, Ventricular Septal Defect Management, and Hemodynamic Assessment
For the American College of Cardiology’s Eagle’s Eye View, Dr. Kim Eagle discusses recent advancements in the management of heart failure (HF). He begins with a state-of-the-art review on iron repletion for patients with HF and iron deficiency. Both the American College of Cardiology/American Heart Association and the European Society of Cardiology now recommend IV iron replacement for these patients to improve functional status and quality of life.
New Insights and Treatments Transform Outlook for Transthyretin Cardiac Amyloidosis
There has been a significant shift in the understanding of heart failure caused by transthyretin cardiac amyloidosis (ATTR-CA). Once thought to be a rare condition, the adoption of nuclear imaging for diagnosis has revealed that ATTR-CA is more common in clinical practice than previously believed. This has been a crucial development as it allows for earlier identification and intervention.
Study Reveals High Kidney Complication Risks for Older Adults After Heart Failure Hospitalization
A cohort study utilized data from the Get With the Guidelines Heart Failure registry, analyzing patient outcomes through Medicare claims data and employing Cox proportional hazards regression models to evaluate the relationship between discharge estimated glomerular filtration rate (eGFR) and subsequent kidney health outcomes.
