An artificial intelligence (AI)-aided study on heart shape, led by Stanford Medicine researchers, found that roundness seems to occur more commonly in healthy hearts than previously believed, but it can also act as a genetic indicator of cardiac problems. AI let researchers demonstrate, at scale, different organ sizes and how they offer important health clues. The study, published in Med, focused on the cone-shaped left ventricle because it is the core part of the heart muscle—and it is susceptible to damage. The researchers concluded that damage not suffered during a heart attack brought about sphericity in this left ventricle, before heart disease has become evident.